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❤️ Nikola Lončar 🐷

"Nikola Lončar (Serbian Cyrillic: Никола Лончар; born May 31, 1972) is a Serbian former professional basketball player. He also holds Spanish citizenship. Professional career Lončar started his career at Partizan, making his professional debut in 1989. With Partizan, he won the Euroleague in 1992. Lončar also played for Real Madrid, Cagiva Varese, PSG Racing, Maccabi Tel Aviv, Joventut Badalona, Zucchetti Montecatini, Breogán, Estudiantes and Armani Jeans Milano. Yugoslav national team Lončar was a member of the Yugoslav national team at four major tournaments during the 1990s. He took silver medal at the 1996 Summer Olympics in Atlanta, United States, gold medal at the 1998 FIBA World Championship in Greece, and two FIBA European Championship medals (gold in 1997 and bronze in 1999). Post-playing After ending his basketball playing career in 2006, Lončar began working on Spanish television as a studio analyst for the NBA coverage on Movistar+ platform. In March 2018, Lončar was named a sports director of Partizan NIS. References External links * Nikola Lončar at acb.com * Nikola Lončar at legabasket.it * Nikola Lončar at euroleague.net * Nikola Lončar at fiba.com Category:1972 births Category:Living people Category:ABA League players Category:Basketball players at the 1996 Summer Olympics Category:CB Breogán players Category:CB Estudiantes players Category:FIBA EuroBasket-winning players Category:Joventut Badalona players Category:KK Partizan players Category:Liga ACB players Category:Maccabi Tel Aviv B.C. players Category:Medalists at the 1996 Summer Olympics Category:Olimpia Milano players Category:Olympic basketball players of Yugoslavia Category:Olympic medalists in basketball Category:Olympic silver medalists for Serbia and Montenegro Category:Pallacanestro Varese players Category:Paris Racing Basket players Category:Real Madrid Baloncesto players Category:Serbian expatriate basketball people in France Category:Serbian expatriate basketball people in Israel Category:Serbian expatriate basketball people in Italy Category:Serbian expatriate basketball people in Spain Category:Serbian men's basketball players Category:Serbian basketball executives and administrators Category:Shooting guards Category:Sportspeople from Kragujevac Category:FIBA World Championship-winning players Category:1998 FIBA World Championship players "

❤️ Padre Hotel 🐷

"The Padre Hotel is a historical landmark hotel located on the corner of 18th and H streets in Bakersfield, California. Originally constructed in 1928 as a luxury hotel and restaurant, the eight-story building recently went through an extensive renovation and reopened in 2010.KBAK News "New owners reveal plans for future of historic Padre Hotel" Published: March 4, 2008 Accessed: Oct 9, 2012 The Padre Hotel features 112 rooms and suites, several meeting spaces, a restaurant, a bar, a cafe, a bistro, and an outdoor bar with a cabana and firepits. The Padre Hotel has an on-site caterer and can accommodate a variety of special events. Guests of the hotel are required to be at least 21 years of age, unless accompanied by an adult.Home Page. The Padre Hotel. Accessed: Oct 9, 2012. History Originally built in 1928, the eight-story Spanish Colonial Revival hotel had an auspicious and flamboyant beginning in the Central Valley’s early and notorious Oil Rush days, but none quite so colorful as that of Milton “Spartacus” Miller, who purchased The Padre in 1954. For the next 45 years, he did spirited battle with Bakersfield’s city fathers over a myriad of issues, even mounting a fake missile on the roof, defiantly directed at City Hall with no small disdain. Miller died in 1999. A fire on the seventh floor in the 1950s resulted in many deaths, including children. Several children were tragically trapped and died in the basement during the 1952 earthquake. There have also been many suicides from the roof of the Padre Hotel. The Padre Hotel fell into disrepair and was a derelict hotel from the 1960s until its most recent renovation in 2010. Prior to that renovation, the upper floors were condemned but often had squatters occupying the rooms. The bar downstairs stayed open during this time and was a meeting place for the city's misfits and barflies. Padre Hotel Bar in the 1980s References Earthquake safety * Earthquake readiness How will Bakersfield stack up to 'the big one' *1952 Kern County earthquake - Wikipedia *Sixty-five years later, 1952 earthquake memories still vivid *1952 Kern County earthquake Legends of haunting * Bakersfield's Historical Haunted Padre Hotel Barry Allen Sunny 105.3 * The Padre Hotel is haunted! Well, maybe * Long Island Medium Theresa Caputo on the road, visits Bakersfield, Hotel Padre, Nashville *Haunted Padre Hotel & Frankenstein Castle The Costa Rican Times *HPI: What We Do in the Shadows *Kern's Most Haunted: Are there ghosts in the Padre Hotel? External links Bakersfieldnow.com: KBAK Bakersfield News article — "New owners reveal plans for future of historic Padre Hotel" (2008) *Youtube.com: KBAK Bakersfield News segment — "Padre Hotel holds grand opening celebration" Category:Hotels in California Category:Buildings and structures in Bakersfield, California Category:Landmarks in Bakersfield, California Category:Hotels established in 1928 Category:Hotel buildings completed in 1928 Category:1928 establishments in California "

❤️ Dual-specificity phosphatase 🐷

"Dual-specificity phosphatase (DUSP; DSP) is a form of phosphatase that can act upon tyrosine or serine/threonine residues. There are several families of dual-specificity phosphatase enzymes in mammals. All share a similar catalytic mechanism, by which a conserved cysteine residue forms a covalent intermediate with the phosphate group to be eliminated. The residues surrounding their catalytic core obey a rather strict consensus: His-Cys-x-x-x-x-x-Arg-Ser. The serine side chain and an additional conserved aspartate play a central role in the elimination of the Cys-linked intermediate, thus completing their enzymatic cycle. The main difference between tyrosine-specific phosphatases and dual-specificity phosphatases lies in the width of the latter enzymes' catalytic pocket: thus they can accommodate phosphorylated serine or threonine side chains as well as phosphorylated tyrosines. Classification The human genome encodes at least 61 different DUSP proteins. The following major groups or families of DUSPs were identified: * Slingshot phosphatases: There are three members of this family (SSH1L, SSH2L and SSH3L) with broad specificity. They contain SH3-binding motifs as well as F-actin binding motifs, thus they are generally believed to play a role in the regulation of cytoskeletal rearrangements. In accordance with their proposed rule, proteins like ADF, cofilin and LIMK1 are slingshot substrates. * Phosphatases of Regenerating Liver (PRLs): Three PRL genes were described in mammals (PRL-1, PRL-2 and PRL-3). They share a high sequence identity and possess an N-terminal prenylation sequence (CAAX box). Despite their up-regulation in colorectal cancer, the role and substrate specificity of PRLs is poorly known. * Cdc14 phosphatases: The four mammalian Cdc14 proteins (named KAP, Cdc14A, Cdc14B and PTP9Q22) play a crucial role in cell cycle regulation by dephosphorylating cyclin-dependent kinases, most importantly CDK2. * PTEN and myotubularin phosphatases There are five PTEN-like phosphatases encoded in the human genome. Though structurally related to other DUSPs, these are not strictly phosphorotein-phosphatases, since their most important substrates are phosphorylated inositol lipids. Myotubularins similarly display a preference towards certain phosphatidyl inositols. * Mitogen-activated protein Kinase Phosphatases (MKPs) MKPs form a rather large family, with some 11 well- characterized members. They are responsible for the dephosphorylation of active mitogen-activated protein kinases (MAPKs). In accordance with this role, several (but not all) MKPs contain an additional, N-terminal domain. Although structurally similar to Cdc14, this extra domain is inactive, and plays a role in substrate recruitment. The surface of this substrate-binding domain mimics the D-motifs found in intrinsically disordered substrates of MAPKs. * In addition, there are several dual-specificity phosphatases lacking close relatives. Most of these atypical DUSPs are poorly characterized. Some of them are probably inactive, and only mediate protein-protein interactions. References Category:Enzymes "

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